Characterisation of a tripartite α-pore forming toxin from Serratia marcescens
نویسندگان
چکیده
منابع مشابه
Chitinases from Serratia marcescens
Serratia marcescens is one of the most effective bacteria for degradation of chitin, a 1,4-β-linked polymer of N-acetyl-β-Dglucosamine (GlcNAc). Chitinolysis by S. marcescens involves at least four enzymes and a chitin-binding protein. Studies of the enzymology and the structures of the enzymes provide insight in how a natural set of chitinolytic enzymes may be built up. S. marcescens chitinase...
متن کاملR factors from Serratia marcescens.
In recent years, Serratia marcescens has become established in certain localities as an agent of hospital infection and cross-infection (Clayton & von Graevenitz, 1966; Wilfert, Barrett & Kass, 1968; Davis, Foltz & Blakemore, 1970; Wilkowske, Washington, Martin & Ritts, 1970). In general, strains of S. marcescens isolated from infective lesions differ from those from other sources in being non-...
متن کاملLysenin: a sphingomyelin specific pore-forming toxin.
Sphingomyelin is a major sphingolipid in mammalian cells. Recent results indicate that sphingomyelin is a reservoir of lipid second messengers, ceramide and sphingosine-1-phosphate. Sphingomyelin is also a major component of sphingolipid and cholesterol-rich membrane domains (lipid rafts). Lysenin is a pore-forming toxin that specifically binds sphingomyelin. The binding of lysenin to sphingomy...
متن کاملProgrammed Cellular Necrosis Mediated by the Pore-Forming α-Toxin from Clostridium septicum
Programmed necrosis is a mechanism of cell death that has been described for neuronal excitotoxicity and ischemia/reperfusion injury, but has not been extensively studied in the context of exposure to bacterial exotoxins. The alpha-toxin of Clostridium septicum is a beta-barrel pore-forming toxin and a potent cytotoxin; however, the mechanism by which it induces cell death has not been elucidat...
متن کاملSerratia marcescens.
Over the last 30 years, Serratia marcescens has become an important cause of nosocomial infection. There have been many reports concerning the identification, antibiotic susceptibility, pathogenicity, epidemiological investigations and typing of this organism. Accurate identification is important in defining outbreaks. The API 20E system has been used widely, but is not individually satisfactor...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2021
ISSN: 2045-2322
DOI: 10.1038/s41598-021-85726-0